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Capítulos
- 00:05Título
- 01:46Pancreatic Duct Ligation (PDL)
- 04:08PDL/Sham Pancreas Tail Harvest
- 05:17Results: PDL Induces Acinar Atrophy and Inflammation without Affecting Bodyweight and Glycemia
- 07:00Conclusion
This protocol describes an injury model involving the surgical ligation of the pancreatic duct in the adult mouse pancreas, resulting in severe injury that establishes an environment that allows beta cell neogenesis and proliferation. This model can be used as a tool to study mechanisms involved in beta cell formation.
