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Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test
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JoVE Journal Medicina
Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test

DOI:
10.3791/52895-v

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06:59 min

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November 13, 2016

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, , , ,
1Cardiovascular and Metabolism Group,Crown Bioscience

Capítulos

  • 00:05Título
  • 00:45Animal Preparation
  • 02:44Intravenous Glucose Tolerance Test (IVGTT) Procedure
  • 04:38Results: Representative IVGTT Glucose Clearance and Insulin Production Curves for Diabetic and Healthy Control Animals
  • 06:17Conclusion

Summary

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The goal of this protocol is to present a standard method to perform intravenous glucose tolerance tests (IVGTTs) to assess glycemic control in nonhuman primates and assess their metabolic status from healthy to dysmetabolic.

Tags

Keywords: Intravenous Glucose Tolerance TestIVGTTMacaquesMetabolic DiseaseInsulin ResistanceDiabetesBlood GlucoseBlood SamplingDextrose InfusionSedated AnimalPulse OximeterRespiratory RateBody TemperatureCatheter PlacementHeparin-saline FlushFasting Blood GlucoseSerum SampleComplete Blood Cell Count

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