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1,6-酮酯高立体选择性合成离子液体介导:三组分反应启用快速进入低分子量胶凝剂的新型类
JoVE Journal
Química
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JoVE Journal Química
Highly Stereoselective Synthesis of 1,6-Ketoesters Mediated by Ionic Liquids: A Three-component Reaction Enabling Rapid Access to a New Class of Low Molecular Weight Gelators
DOI:

06:31 min

November 27, 2015

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Capítulos

  • 00:05Título
  • 01:14Gram-scale Synthesis of Methyl 6-oxo-3,4,6-triphenylhexanoate
  • 03:34Recycling of EMIMAc and Gelation
  • 04:36Results: Analysis of Three-component Synthesis of 1,6-Ketoester
  • 05:35Conclusion

Summary

Tadução automática

Ionic liquids (ILs) mediate fast, simple and cheap access to 1,6-ketoesters in high diastereoselectivities and good yields. The reaction protocol is robust and the 1,6-ketoesters can be obtained in gram scale after a simple filtration protocol. Moreover, the 1,6-ketoesters are potent gelators in hydrocarbon solvents.

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