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研究小鼠GPCR异聚的行为功能嵌合构造的HSV介导的转基因表达
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Neurociência
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JoVE Journal Neurociência
HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice
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研究小鼠GPCR异聚的行为功能嵌合构造的HSV介导的转基因表达

DOI:
10.3791/53717-v

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07:30 min

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July 09, 2016

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, ,
1Department of Psychiatry,Icahn School of Medicine at Mount Sinai, 2Department of Neurology,Icahn School of Medicine at Mount Sinai, 3Friedman Brain Institute,Icahn School of Medicine at Mount Sinai, 4Department of Physiology and Biophysics,Virginia Commonwealth University Medical School

Capítulos

  • 00:05Título
  • 00:56Stereotaxic Surgery to Introduce HSV Chimeric Constructs
  • 03:32Head Twitch Response Experiment
  • 05:04Data Review
  • 05:33Resultados
  • 06:35Conclusion

Summary

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Tadução automática

本文介绍如何注入病毒载体插入鼠标额叶皮质测试需要GPCR异形成行为检测。

Tags

HSVTransgene ExpressionGPCR HeteromersMouse ModelBehavioral PhenotypesSerotonin 2aMetabotropic Glutamate Receptor 2Stereotactic SurgeryVirus-mediated Gene TransferAnesthesiaInjectionFrontal Cortex

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