Journal
/
Química
/
Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier
JoVE Journal
Química
É necessária uma assinatura da JoVE para visualizar este conteúdo.  Faça login ou comece sua avaliação gratuita.
JoVE Journal Química
Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier

Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier

DOI:
10.3791/53760-v

•

07:53 min

•

April 26, 2016

•

,
1Institute of Environment, Health, Risks and Futures,Cranfield University

Capítulos

  • 00:05Título
  • 00:53Optimization of Emulsion Conditions
  • 03:21Preparation of Dacarbazine-loaded NLC
  • 04:35Results: Encapsulation of Dacarbazine Using NLC to Improve Therapeutic Profiling
  • 05:59Conclusion

Summary

Tadução automática

Tadução automática

The most commonly used method for nanostructured lipid carrier (NLC) synthesis involves oil-in-water emulsion, homogenization and solidification. This was modified here by applying high shear dispersion after solidification to achieve a NLC with desirable size, improved drug encapsulation and drug loading efficiency as a potential carrier for dacarbazine delivery.

Tags

Keywords: Nanostructured Lipid CarrierDacarbazineCancer Therapeutic AgentEncapsulationDrug DispersityDrug Release ControlEmulsionHomogenizationDynamic Light ScatteringTransmission Electron Microscopy

Article

Embed

ADICIONAR À PLAYLIST

Usage Statistics

Vídeos Relacionados

check_url/pt/53760?article_type=v

Untargeted Metabolomics from Biological Sources Using Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry (UPLC-HRMS)
check_url/pt/53760?article_type=v

Isolation and Chemical Characterization of Lipid A from Gram-negative Bacteria
check_url/pt/53760?article_type=v

Quantitative Proteomics Using Reductive Dimethylation for Stable Isotope Labeling
check_url/pt/53760?article_type=v

A Colorimetric Assay that Specifically Measures Granzyme B Proteolytic Activity: Hydrolysis of Boc-Ala-Ala-Asp-S-Bzl
check_url/pt/53760?article_type=v

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes
check_url/pt/53760?article_type=v

NMR Spectroscopy as a Robust Tool for the Rapid Evaluation of the Lipid Profile of Fish Oil Supplements
check_url/pt/53760?article_type=v

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding
check_url/pt/53760?article_type=v

Analysis of Minerals Produced by hFOB 1.19 and Saos-2 Cells Using Transmission Electron Microscopy with Energy Dispersive X-ray Microanalysis
check_url/pt/53760?article_type=v

Organic Structure-directing Agent-free Synthesis for *BEA-type Zeolite Membrane
check_url/pt/53760?article_type=v

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro

Read Article