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Capítulos
- 00:05Título
- 00:57Pancreas Perfusion
- 01:54Pancreas Dissociation
- 03:41Islet Purification
- 05:55Islet Cell Dispersion and Plating and Culture Treatment
- 08:06Results: Dipyridamole Treatment Induces Beta- But Not Alpha-cell Replication
- 08:48Conclusion
Critical challenges for the diabetes research field are to understand the molecular mechanisms that regulate islet β-cell replication and to develop methods for stimulating β-cell regeneration. Herein a high-content screening method to identify and assess the β-cell replication-promoting activity of small molecules is presented.
