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A Robust Pneumonia Modell in intaktem Immunsystem Nagetiere zur Bewertung antibakterieller Wirksamkeit gegen<i> S. pneumoniae</i>,<i> H. influenzae</i>,<i> K. pneumoniae</i>,<em> P. aeruginosa</em> oder<em> A. baumannii</em
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Capítulos
- 00:05Título
- 01:13Prepare Saline Bacterial Suspensions and Agar-based Inoculum
- 02:20Prepare Intubation Device, Intubate and Inoculate Rats
- 05:47Prepare Intubation Device, Intubate, and Inoculate Mice
- 07:10Results: Evaluation of Antibacterial Efficacy in Infected Rats and Mice
- 08:37Conclusion
A method for establishing lung infections in immunocompetent rodents is described. With proficiency, this method can be performed quickly and easily to induce stable infection with many isolates of S. pneumoniae, H. influenzae, P. aeruginosa, K. pneumoniae and A. baumannii.
Tags
Keywords:
Pneumonia ModelImmunocompetent RodentsAntibacterial EfficacyS. PneumoniaeH. InfluenzaeK. PneumoniaeP. AeruginosaA. BaumanniiIntrabronchial InfectionBacterial PneumoniaImmunocompetent ModelRobust And Reproducible Lung InfectionIntubationTracheaBacterial SuspensionAgar PlatesSalineSerial DilutionAgarWater BathIntubation Device
