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Hydrolysis of a Ni-Schiff-Base Complex Using Conditions Suitable for Retention of Acid-labile Protecting Groups
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Capítulos
- 00:05Título
- 00:57Hydrolysis of Ni-Schiff-Base Complex
- 02:05Fmoc Protection of Hydrolyzed Amino Acid
- 03:57Resultados
- 05:32Conclusion
Here, we present an efficient hydrolysis and subsequent Fmoc protection of an amino acid isolated from a Ni-Schiff-base complex. Hydrolysis conditions presented here are suitable for use when retention of acid-labile side-chain protecting groups is required. This technique may be adaptable to a variety of unnatural amino acid substrates.
