É necessária uma assinatura da JoVE para visualizar este conteúdo. Faça login ou comece sua avaliação gratuita.
1Research Service,VA Western New York Healthcare System, 2Department of Ophthalmology, (Ross Eye Institute), Jacobs School of Medicine and Biomedical Sciences,University at Buffalo- SUNY, 3Pharmacology/Toxicology, Jacobs School of Medicine and Biomedical Sciences,University at Buffalo- SUNY, 4Physiology/Biophysics, Jacobs School of Medicine and Biomedical Sciences,University at Buffalo- SUNY, 5Neuroscience Program, Jacobs School of Medicine and Biomedical Sciences,University at Buffalo- SUNY, 6The RNA Institute,University at Buffalo- SUNY, 7The SUNY Eye Institute
Capítulos
- 00:04Título
- 00:45Subretinal Injection
- 02:37Injection Site and Subretinal Bleb Mapping
- 04:03High Resolution Spectral-Domain Optical Coherence Tomography (HR-SD-OCT) Outer Retinal Degeneration Evaluation
- 07:47Results: Representative Outer Retinal Change Quantification and Post-Subretinal Injection 3D Mapping
- 08:54Conclusion
यहां हम उच्च संकल्प वर्णक्रमीय-डोमेन ऑप्टिकल जुटना टोमोग्राफी (मानव संसाधन एसडी अक्टूबर) का उपयोग करने के लिए एक उपंयास दृष्टिकोण प्रदर्शित करने के लिए रेटिना अंतरिक्ष में जीन थेरेपी एजेंटों के वितरण की सहायता, अपने आरईएल कवरेज का आकलन है, और photoreceptor जीवन शक्ति की विशेषता ।
Tags
Ultrahigh ResolutionMouseOptical Coherence TomographyIntraocular InjectionRetinal Gene TherapySubretinal InjectionVector DeliveryTherapeutic Agent ToxicityMinimally InvasiveReproducibleReal-time ObservationRetinal ImagingProptosisScleral DepressionRetinal Pigment EpitheliumSubretinal SpaceInjection OutcomesOCT Imaging
