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Cardiopulmonary Bypass in a Mouse Model: A Novel Approach
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JoVE Journal Medicina
Cardiopulmonary Bypass in a Mouse Model: A Novel Approach

Cardiopulmonary Bypass in a Mouse Model: A Novel Approach

DOI:
10.3791/56017-v

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08:08 min

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September 22, 2017

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, , , , , , , , , , , , , ,
1Department of Cardiothoracic, Transplantation, and Vascular Surgery,Hannover Medical School, 2Department of Hematology, Oncology, Immunology, Rheumatology, and Pulmonology,University Hospital Tuebingen, 3Department of Pneumology,Hannover Medical School

Capítulos

  • 00:05Título
  • 00:50Surgical Equipment Preparations
  • 01:56Surgery: Preparing for the Cardiopulmonary Bypass
  • 04:56Surgery: Cardiopulmonary Bypass Blood Gass Analysis (BGA)
  • 06:25Results: BGA Measurements
  • 07:13Conclusion

Summary

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This paper describes how to perform cardiopulmonary bypass in mice. This novel model will facilitate the investigation of the molecular mechanisms involved in organ damage.

Tags

Keywords: Cardiopulmonary BypassMouse ModelCardiac SurgeryMolecular MechanismsHeart DamageNon-survival Acute ModelVenous CannulaPriming SolutionFemoral ArteryJugular VeinCarotid ArterySilk SuturesMicro Surgical ForcepsBipolar ForcepsCoagulator

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