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División ingeniería-TET2 enzima ADN químico-inducible Hydroxymethylation y remodelación epigenéticos
 
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División ingeniería-TET2 enzima ADN químico-inducible Hydroxymethylation y remodelación epigenéticos

Article DOI: 10.3791/56858-v • 08:34 min • December 18th, 2017
December 18th, 2017 •
1, 2, 1
1Centre for Epigenetics and Disease Prevention, Department of Molecular and Cellular Medicine, Institute of Biosciences and Technology, College of Medicine, Texas A&M University, 2Centre for Translational Cancer Research, Department of Medical Physiology, Institute of Biosciences and Technology, College of Medicine, Texas A&M University

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Protocolos detallados para la introducción de una enzima de la división ingeniería-TET2 (sidra) en células de mamífero para químicas inducible hydroxymethylation de ADN y remodelación epigenéticos se presentan.

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Química número 130 la metilación del ADN epigenética accesibilidad de cromatina desmetilación del ADN Biología química TET2 5-hidroximetilcitosina transcripción expresión génica edición de epigenoma
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