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Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
 

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery

Article DOI: 10.3791/57229-v • 09:12 min • March 27th, 2018
March 27th, 2018 •
1, 1, 1, 1, 1, 2, 1
1Department of Surgery, University of Minnesota, 2Cardiology, Minneapolis VA Medical Center

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This protocol presents a surgical large animal model of chronic, single vessel ischemia that results in regional abnormalities but does not create infarct, known as hibernating myocardium. Following establishment of chronic ischemia, animals are treated with off-pump LIMA-LAD coronary artery bypass graft surgery to revascularize the ischemic tissue.

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Keywords: Surgical Swine Model Chronic Cardiac Ischemia Off-pump Coronary Artery Bypass Graft Surgery Cardiothoracic Surgery Hibernating Myocardium Left Anterior Descending Artery Coronary Artery Constrictor Bypass Graft Revascularization Atherosclerotic Disease
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