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小鼠活动性厌食症的评估

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JoVE Journal Comportamento

Assessing Activity-based Anorexia in Mice

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小鼠活动性厌食症的评估

DOI:

10.3791/57395-v

•

08:26 min

•

May 14, 2018

•

Amanda C. Welch, William R. Katzka², Stephanie C. Dulawa

¹Department of Psychiatry,University of California, San Diego, ²University of California, Los Angeles

Capítulos

00:04Título
00:41Set Up and Pre-experimental Acclimation Phase – Days 1 and 2
03:13Experimental Baseline Phase – Days 3 to 9
05:23Experimental Restriction Phase – Days 11 to 23
06:39Results: Assessing Biochemical Consequences of Activity-based Anorexia
07:44Conclusion

Summary

Tadução automática

老鼠单独安置与一个奔跑的轮子, 当获得食物的有限的获取开发减少食物消耗量和增加活动在奔跑的轮子。这种实验性的现象叫做活动性厌食症。这个范式为研究神经性厌食症的生物学和行为提供了一个实验工具。

Tags

Anorexia Nervosa Activity-based Anorexia Mouse Model Neurobiology Eating Disorders Running Wheel Food Restriction Behavioral Assessment

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