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心内神经元对体外 Langendorff 系统心脏电生理和心脏交感神经的影响

JoVE Journal
Medicina

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JoVE Journal Medicina

Impact of Intracardiac Neurons on Cardiac Electrophysiology and Arrhythmogenesis in an Ex Vivo Langendorff System

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心内神经元对体外 Langendorff 系统心脏电生理和心脏交感神经的影响

DOI:

10.3791/57617-v

•

06:40 min

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May 22, 2018

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Christiane Jungen², Katharina Scherschel², Nadja I. Bork³, Pawel Kuklik, Christian Eickholt, Helge Kniep, Niklas Klatt², Stephan Willems², Viacheslav O. Nikolaev³, Christian Meyer²

¹Department of Cardiology-Electrophysiology, cNEP (cardiac Neuro- and Electrophysiology research group), University Heart Center,University Hospital Hamburg-Eppendorf, ²DZHK (German Center for Cardiovascular Research), ³Institute of Experimental Cardiovascular Research,University Medical Center Hamburg-Eppendorf

Capítulos

00:04Título
00:47Preparation of Langendorff Apparatus & Heart
02:21Electrophysiological Parameters and Arrhythmogenesis
03:16Förster Resonance Energy Transfer (FRET)-based Cyclic Adenosine Monophosphate (cAMP) Imaging
04:51Results: The Langendorff Ex Vivo Heart Perfusion System is Useful to Study the Impact of Intracardiac Electrophysiology and Arrhythmogenesis
06:07Conclusion

Summary

Tadução automática

在这里, 我们提出了一个调节心内自主神经系统的协议, 并评估其对基本的电生理, 心脏交感神经和阵营动力学的影响使用前体 Langendorff 设置.

Tags

Keywords: Intracardiac Neurons Cardiac Electrophysiology Arrhythmogenesis Langendorff System Autonomic Nervous System CAMP Dynamics Electrophysiology Catheter Programmed Stimulation Ventricular Arrhythmogenesis Multi-electrode Array

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