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1Department of Neurobiology, F. M. Kirby Neurobiology Center,Boston Children’s Hospital, Harvard Medical School, 2Proteomic Mass Spectrometry,Wellcome Trust Sanger Institute, Wellcome Genome Campus, 3Centre for Molecular Informatics, Department of Chemistry,University of Cambridge, 4Functional Proteomics Group, Chester Beatty Laboratories,Institute of Cancer Research
Capítulos
- 00:05Título
- 00:51Mapping of Peptides using PoGoGUI
- 02:36Visualizing in the Integrative Genomics Viewer
- 03:57Mapping Peptides Identified Through a Custom Variant Database to a Reference Genome
- 04:44Mapping Peptides from Multiple Files Using PoGoGUI
- 05:48Generating a Track Hub from Mapped Peptides and Visualizing a Track Hub in the UCSC Genome Browser
- 06:50Results: Post-translational Modification and Varient Enabled Mapping of Peptides to Genomes
- 08:21Conclusion
Aquí presentamos la herramienta proteogenomic PoGo y protocolos para la modificación rápida, cuantitativo, poste-de translación y variante activado mapeo de péptidos identificados a través de espectrometría de masas en los genomas de referencia. Esta herramienta es de uso para integrar y visualizar proteogenomic y estudios proteómicos personal con datos de genómica ortogonal.
