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Syntese av 68Ga Core-dopet jernoksid nanopartikler dobbelt fantes et Positron utslipp stengte / (T1) magnetisk resonans Imaging
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Biologia
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JoVE Journal Biologia
Synthesis of 68Ga Core-doped Iron Oxide Nanoparticles for Dual Positron Emission Tomography /(T1)Magnetic Resonance Imaging

Syntese av 68Ga Core-dopet jernoksid nanopartikler dobbelt fantes et Positron utslipp stengte / (T1) magnetisk resonans Imaging

DOI:
10.3791/58269-v

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07:26 min

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November 20, 2018

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, , ,
1Nanobiotechnology, Molecular Imaging and Metabolomics Lab,Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 2CIC biomaGUNE and CIBER de Enfermedades Respiratorias (CIBERES). Ikerbasque, Basque Foundation for Science,Universidad Complutense de Madrid (UCM), 3Advanced Imaging Unit, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC),CIBER de Enfermedades Respiratorias (CIBERES)

Capítulos

  • 00:04Título
  • 00:26Synthesis of Citrate-Coated Iron Oxide Nanoparticles
  • 01:41Synthesis of 68Ga Core-Doped Iron Oxide Nanoparticles (68Ga-C-IONP)
  • 03:19Analysis of 68Ga Core-Doped Iron Oxide Nanoparticles (68Ga-C-IONP)
  • 04:42Results: Characterization of 68Ga Core-Doped Iron Oxide Nanoparticles
  • 06:40Conclusion

Summary

Tadução automática

Tadução automática

Her presenterer vi en protokoll for å få68Ga core-dopet jernoksid nanopartikler via fast mikrobølgeovn-drevet syntese. Metodikken gjengir PET / (T1) MRI nanopartikler med radiolabeling effektivitet høyere enn 90% og radiochemical renhet 99% i en 20 minutters syntese.

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Keyword Extraction: 68GaCore-dopedIron Oxide NanoparticlesDual PET/MR ImagingMicrowave SynthesisReproducibleIron Chloride HexahydrateCitric Acid Trisodium Salt DihydrateHydrazine HydrateGel Filtration Desalting ColumnGallium-68 GeneratorGallium-68 ChlorideHydrodynamic Size

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