Journal
/
Medicina
/
Induktion af aterosklerotiske Plaques gennem aktivering af Mineralocorticoid receptorer i Apolipoprotein E-mangelfuld mus
JoVE Journal
Medicina
É necessária uma assinatura da JoVE para visualizar este conteúdo.  Faça login ou comece sua avaliação gratuita.
JoVE Journal Medicina
Induction of Atherosclerotic Plaques Through Activation of Mineralocorticoid Receptors in Apolipoprotein E-deficient Mice

Induktion af aterosklerotiske Plaques gennem aktivering af Mineralocorticoid receptorer i Apolipoprotein E-mangelfuld mus

DOI:
10.3791/58303-v

•

07:36 min

•

September 26, 2018

•

, , , ,
1Laboratory of Cardiovascular Endocrinology,IRCCS San Raffaele Pisana, Rome, Italy, 2Department of Human Sciences and Promotion of the Quality of Life,San Raffaele Roma Open University, Rome, Italy

Capítulos

  • 00:04Título
  • 00:45Osmotic Pump Filling and Implantation
  • 02:38Heart Dissection
  • 04:03Aortic Root Sectioning and Oil Red O Neutral Fat Staining
  • 05:47Results: Evaluation of the Aortic Root Phenotype in Aldosterone-induced Atherosclerosis in Apolipoprotein-E Knockout (ApoE -/-) Mice
  • 06:28Conclusion

Summary

Tadução automática

Tadução automática

Vi beskriver en protokol for at fremkalde åreforkalkning i aorta roden af ApoE- / - mus fodret med en atherogene kost, gennem en kontinuerlig frigivelse af aldosteron. Metoder til at karakterisere plaque sammensætning er også beskrevet.

Tags

Keywords: AtherosclerosisApolipoprotein E-deficient MiceMineralocorticoid ReceptorsAldosteroneMini-pump ImplantationAtherosclerotic Plaque InductionPerfusion

Article

Embed

ADICIONAR À PLAYLIST

Usage Statistics

Vídeos Relacionados

check_url/pt/58303?article_type=v

Delivery of Therapeutic Agents Through Intracerebroventricular (ICV) and Intravenous (IV) Injection in Mice
check_url/pt/58303?article_type=v

Induktion af Invasive Transitional Cell blærecarcinom i Immune intakt humant MUC1 transgene mus: En model for immunterapi Development
check_url/pt/58303?article_type=v

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus
check_url/pt/58303?article_type=v

Produktion af Apolipoprotein C-III Knockout Kaniner hjælp zinkfinger Nucleaser
check_url/pt/58303?article_type=v

Profilering af østrogen-regulerede MicroRNA i brystkræftceller
check_url/pt/58303?article_type=v

Halspulsåren infusioner farmakokinetisk og farmakodynamisk analyse af Taxaner i mus
check_url/pt/58303?article_type=v

Bile Duct Ligering i mus: Induktion af inflammatorisk leverskade, og fibrose ved Obstruktiv Kolestase
check_url/pt/58303?article_type=v

Induktion af accelereret åreforkalkning i Mus: Den "Wire-Skade" Model
check_url/pt/58303?article_type=v

Teknik, minimalt Invasive tværgående aorta konstriktion i mus til induktion af venstre ventrikel hypertrofi
check_url/pt/58303?article_type=v

Induktion af Nefrotisk syndrom hos mus ved retrobulbær injektion af Doxorubicin og forebyggelse af volumen opbevaring af vedvarende frigivelse Aprotinin

Read Article