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1SOFIE, 2Department of Molecular & Medical Pharmacology,David Geffen School of Medicine, University of California, Los Angeles (UCLA), 3Ahmanson Translational Imaging Division,University of California, Los Angeles (UCLA), 4Crump Institute for Molecular Imaging,University of California, Los Angeles (UCLA)
Capítulos
- 00:04Título
- 00:53Synthesis Protocol Automation
- 02:13Setup for Automated Synthesis
- 05:25Automated Synthesis, Purification and Formulation, and Post-Run System Shutdown
- 09:10Results: Representative Quality Control Test Data Summary for Three Validation Batches
- 09:33Conclusion
Positron-emissions-tomografi (PET) imaging websteder, der er involveret i flere tidlige klinisk forskning forsøg har brug for robuste og alsidige radiotracer fremstilling kapaciteter. Ved hjælp af radiotracer [18F] BSA som et eksempel, vi illustrere hvor hen til automatisere syntesen af en radiotracer ved hjælp af en fleksibel, kassette-baserede radiosynthesizer og validere syntese til klinisk brug.
