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几内亚猪模型心肌损伤后 hiPSC-derived 衍生心肌贴片的植入

JoVE Journal
Medicina

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JoVE Journal Medicina

Implantation of hiPSC-derived Cardiac-muscle Patches after Myocardial Injury in a Guinea Pig Model

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几内亚猪模型心肌损伤后 hiPSC-derived 衍生心肌贴片的植入

DOI:

10.3791/58810-v

•

07:03 min

•

March 18, 2019

•

Liesa Castro², Birgit Geertz, Marina Reinsch³, Bülent Aksehirlioglu, Arne Hansen³, Thomas Eschenhagen³, Hermann Reichenspurner², Florian Weinberger*^2,3, Simon Pecha*^1,2

¹Department of Cardiovascular Surgery,University Heart Center Hamburg, ²partner site Hamburg/Kiel/Lübeck,German Centre for Cardiovascular Research (DZHK), ³Department of Experimental Pharmacology and Toxicology, Cardiovascular ResearchCenter,University Medical Center Hamburg-Eppendorf

Capítulos

00:04Título
00:33Transthoracic Echocardiography
01:27Myocardial Infarction Induction
04:10Engineered Heart Tissue (EHT) Implantation
05:21Results: Representative Human Engineered Heart Tissue (hEHT) Patch Analyses
06:05Conclusion

Summary

Tadução automática

在这里, 我们提出了一个方案, 诱导左心室内皮损伤, 然后植入心肌贴片, 从人类 ips 细胞心肌细胞在豚鼠模型中获得。

Tags

Keywords: HiPSC-derived Cardiac-muscle Patches Myocardial Injury Guinea Pig Model Cryoinfarction Model Echocardiography Tracheal Intubation Thoracotomy Left Ventricular Cryoinjury

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