Journal
/
Imunologia e Infecção
/
人正常记忆 b 细胞与长寿浆细胞体外分化模型
JoVE Journal
Imunologia e Infecção
É necessária uma assinatura da JoVE para visualizar este conteúdo.  Faça login ou comece sua avaliação gratuita.
JoVE Journal Imunologia e Infecção
In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
Please note that all translations are automatically generated. Click here for the English version.

人正常记忆 b 细胞与长寿浆细胞体外分化模型

DOI:
10.3791/58929-v

•

10:26 min

•

January 20, 2019

•

, , , ,
1IGH, CNRS,Univ Montpellier, 2Laboratory for Monitoring Innovative Therapies, Department of Biological Hematology,CHU Montpellier, 3UFR de Médecine,Univ Montpellier

Capítulos

  • 00:04Título
  • 00:52B Cell Amplification and Differentiation
  • 03:44Plasmablastic Cell Generation
  • 04:36Early Plasma Cell Generation
  • 05:21Long-lived Plasma Cell Generation
  • 06:29Molecular Atlas of B to PC Differentiation
  • 07:33Results: Epigenetic Factor Expression in Normal Plasma Cell Differentiation
  • 09:01Conclusion

Summary

Tadução automática

Tadução automática

利用多步培养系统, 我们报告了体外 b 细胞对血浆细胞分化模型。

Tags

In Vitro DifferentiationHuman Normal Memory B CellsLong-lived Plasma CellsPlasma Cell DifferentiationB2 Plasma Cell DifferentiationTranscriptional ChangesPhenotypeBioinformatic ToolsMemory B Cell PurificationCD40 LigandAnti-polyhistidine Monoclonal Antibody

Article

Embed

ADICIONAR À PLAYLIST

Usage Statistics

Vídeos Relacionados

激活的B细胞CD40的小鼠模型

从初级人类的幼稚和记忆T细胞的诱导调节性T细胞的生成

一个<em>在体外</em>共感染模型研究<em>恶性疟原虫</em人原发性单核细胞源性的免疫细胞-HIV-1相互作用

一个<em在体外</em>模型研究人类巨噬细胞分化和极化的异质性

量<em在体外</em>激活的主人微血管内皮细胞在静态条件下测量的检测，以中性粒细胞粘附

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection

从排序的永生B细胞产生的重组人IgG单克隆抗体

的分离，分化和人类的定量分泌抗体的B细胞从血液：酶联免疫斑点作为体液免疫的功能读出

在从幼稚的CD4 + T细胞的人CD4 + FOXP3 +诱导调节性T细胞（iTregs的）使用含有TGF-β-协议的体外分化

HDAC 抑制剂介导的 B 细胞 rna 和基因的基因组分析--诱导进行类开关 DNA 重组和血浆细胞分化

Read Article