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利用斑马鱼胚胎对化合物毒性的快速评价

JoVE Journal
Medicina

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JoVE Journal Medicina

Rapid Evaluation of Toxicity of Chemical Compounds Using Zebrafish Embryos

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利用斑马鱼胚胎对化合物毒性的快速评价

DOI:

10.3791/59315-v

•

00:07 min

•

August 25, 2019

•

Ashok Aspatwar, Milka Marjut Hammaren, Mataleena Parikka², Seppo Parkkila³

¹Faculty of Medicine and Health Technology,Tampere University, ²Oral and Maxillofacial Unit,Tampere University Hospital, ³Fimlab Ltd,Tampere University Hospital

Capítulos

00:04Título
01:33Collection of Embryos
02:48Exposure to Toxicity
04:09Phenotypic Analysis
05:28Results: Toxicity Analysis
06:51Conclusion

Summary

Tadução automática

斑马鱼胚胎用于评估化合物的毒性。它们从外部发展，对化学品敏感，能够检测细微的型型变化。实验只需要少量的化合物，直接添加到含有胚胎的板中，使测试系统高效且经济高效。

Tags

Keywords: Zebrafish Embryos Toxicity Testing Chemical Compounds Rapid Evaluation Off-target Effects Tuberculosis Phenotypic Changes Embryo Medium Breeding Mating Tanks

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