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Investigating Alterations in Caecum Microbiota After Traumatic Brain Injury in Mice
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Neurociência
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JoVE Journal Neurociência
Investigating Alterations in Caecum Microbiota After Traumatic Brain Injury in Mice

Investigating Alterations in Caecum Microbiota After Traumatic Brain Injury in Mice

DOI:
10.3791/59410-v

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04:29 min

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September 19, 2019

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, , , , ,
1Emergency and Trauma Center, The International Medical Center, The First Affiliated Hospital, School of Medicine,Zhejiang University

Capítulos

  • 00:04Título
  • 00:48Traumatic Brain Injury (TBI) Induction
  • 02:56Laparotomy and Caecum Sample Collection
  • 03:29Results: Representative Caecum Microbiota Diversity After TBI
  • 03:57Conclusion

Summary

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Presented here is a protocol to induce diffuse traumatic brain injury using a lateral fluid percussion device followed by the collection of the caecum content for gut microbiome analysis.

Tags

Traumatic Brain InjuryCaecum MicrobiotaGut-brain AxisLateral Fluid Percussion InjuryMouse ModelMicrobiome Analysis

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