Journal
/
Neurociência
/
通过对流增强的传递将抗体输送到毛里脑
JoVE Journal
Neurociência
É necessária uma assinatura da JoVE para visualizar este conteúdo.  Faça login ou comece sua avaliação gratuita.
JoVE Journal Neurociência
Delivery of Antibodies into the Murine Brain via Convection-enhanced Delivery
Please note that all translations are automatically generated. Click here for the English version.

通过对流增强的传递将抗体输送到毛里脑

DOI:
10.3791/59675-v

•

08:22 min

•

July 18, 2019

•

, , ,
1Institute of Laboratory Animal Science,University of Zurich

Capítulos

  • 00:04Título
  • 00:49Step Catheter Preparation
  • 02:29Step Catheter Testing
  • 04:46Antibody Solution Convection-enhanced Delivery (CED) into the Murine Brain
  • 06:34Results: Representative CED Infusion Analyses
  • 07:40Conclusion

Summary

Tadução automática

Tadução automática

对流增强输送(CED)是一种通过直接灌注大量组织,使治疗药物有效输送到大脑的方法。该过程需要使用导管和优化的注射程序。该协议描述了一种将抗体送入小鼠大脑的CED方法。

Tags

Keywords: Convection-enhanced DeliveryAntibody DeliveryBrainMurineStep CatheterBlood-brain BarrierFused Silica CapillaryCyanoacrylate AdhesiveStereotactic RobotAgarose GelTrypan Blue

Article

Embed

ADICIONAR À PLAYLIST

Usage Statistics

Vídeos Relacionados

check_url/pt/59675?article_type=v

定向脑深部结构与配送药品，病毒载体，或细胞移植Microinjections
check_url/pt/59675?article_type=v

基因传递到产后大鼠脑非心室质粒注射和电穿孔
check_url/pt/59675?article_type=v

高效的基因传递到多个中枢神经系统使用新界在子宫内电穿孔
check_url/pt/59675?article_type=v

啮齿动物的中枢神经系统药物直接脑室交货
check_url/pt/59675?article_type=v

低聚淀粉样蛋白-β的立体灌注到小鼠海马
check_url/pt/59675?article_type=v

Miniosmotic植入泵和交货道示踪研究在病理情况下脑重组
check_url/pt/59675?article_type=v

设计，包装，并通过立体定向注射高效价CRISPR复古和慢交付
check_url/pt/59675?article_type=v

鼠标显微注水技术进行有针对性的物质传递到中枢神经系统<i>通过</i>的颈内动脉
check_url/pt/59675?article_type=v

荧光标记蛋白 ImageJ 的无偏分析在果蝇变性定量细胞生物学中的应用
check_url/pt/59675?article_type=v

在在线 MRI 图像的指导下,对流增强将视遗传阿德诺相关病毒载体输送到 Rhesus Macaque 的皮质

Read Article