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Capítulos
- 00:04Título
- 00:50Brain Dissection and Trimming
- 02:52Brain Slicing
- 04:10Whole-Cell Patch-Clamp Recording
- 06:10Long Term Depression (LTD) Induction
- 07:12Results: Representative Purkinje Cell Voltage and Current Traces During Conjunctive Stimulation
- 08:44Conclusion
In some gene-manipulated animals, using a single protocol may fail to induce LTD in cerebellar Purkinje cells, and there may be a discrepancy between LTD and motor learning. Multiple protocols are necessary to assess LTD-induction in gene-manipulated animals. Standard protocols are shown.
