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研究小鼠心肌梗死的低温损伤模型

JoVE Journal
Medicina

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JoVE Journal Medicina

A Cryoinjury Model to Study Myocardial Infarction in the Mouse

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研究小鼠心肌梗死的低温损伤模型

DOI:

10.3791/59958-v

•

06:29 min

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September 19, 2019

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Dong Wang*^1,2, Grigol Tediashvili*^1,2, Xiaomeng Hu², Alessia Gravina, Sivan G. Marcus², Hao Zhang, Jeffrey E Olgin, Tobias Deuse^2,5, Sonja Schrepfer^2,3,5

¹Transplant and Stem Cell Immunobiology Lab,University Heart Center, ²Department of Surgery, Transplant and Stem Cell Immunobiology Lab,University of California San Francisco, ³Cardiovascular Research Center (CVRC) and DZHK German Center for Cardiovascular Research, ⁴Division of Cardiology, Cardiovascular Research Institute,University of California San Francisco, ⁵Cardiovascular Surgery,University Heart Center

Capítulos

00:04Título
00:52Mouse Preparation
04:28Results: Representative Functional, Electrophysiological, and Histological Cryoinjured Heart Analyses
05:47Conclusion

Summary

Tadução automática

本文演示了研究小鼠心肌低温损伤后心脏重塑的模型。

Tags

Cryoinjury Model Myocardial Infarction Mouse Cardiac Recovery Stem Cell Transplantation Experimental Interventions Pharmacological Strategies Large Animal Models Anesthesia Tracheotomy Ventilation Rib Dissection Pericardial Exposure Cryoprobe Left Ventricular Infarct

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