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Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
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Neurociência
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JoVE Journal Neurociência
Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury

DOI:
10.3791/60012-v

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10:33 min

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August 14, 2019

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, ,
1Infinity lab, Medical Imaging and Signal Processing Group,Ghent University

Capítulos

  • 00:04Título
  • 01:01Animal Preparation and Helmet Attachment
  • 01:54Traumatic Brain Injury (TBI)
  • 03:03Diffusion Magnetic Resonance Imaging (MRI)
  • 05:48Image Processing
  • 07:59Results: Representative Changes in Hippocampal Diffusion Tenor and Kurtosis Metrics After Mild TBI
  • 09:47Conclusion

Summary

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The overall goal of this procedure is to obtain quantitative microstructural information of the hippocampus in a rat with mild traumatic brain injury. This is done using an advanced diffusion-weighted magnetic resonance imaging protocol and region-of-interest based analysis of parametric diffusion maps.

Tags

Diffusion ImagingHippocampusMild Traumatic Brain InjuryMicrostructural ChangesPreclinical StudiesDementiaMultiple SclerosisWistar H RatLidocaineSkullBrass WeightCT ScanRecumbency

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