Journal
/
/
Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen
JoVE Journal
Medicina
Author Produced
É necessária uma assinatura da JoVE para visualizar este conteúdo.  Faça login ou comece sua avaliação gratuita.
JoVE Journal Medicina
Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen
DOI:

09:44 min

November 27, 2019

, , , , , , , , , ,

Capítulos

  • 00:00Título
  • 01:54Procedimento
  • 02:13Pre-operative Procedures
  • 03:12Partial Hepatectomy to Remove 70% Liver Mass
  • 05:38Post-operative Care
  • 06:35Injection of Drug in Partially Hepatectomized Animals to induce Liver Failure
  • 06:58Resultados
  • 09:19Conclusion

Summary

Tadução automática

The acute liver failure animal model developed in the current study presents a feasible alternative for the study of potential therapies. The current model employs the combined effect of physical and drug-induced hepatic injury and provides a suitable time window to study the potential of novel therapies.

Vídeos Relacionados

Read Article