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En præklinisk rotte model for studiet af iskæmi-reperfusion skade i rekonstruktiv mikrokirurgi
JoVE Journal
Medicina
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JoVE Journal Medicina
A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery

En præklinisk rotte model for studiet af iskæmi-reperfusion skade i rekonstruktiv mikrokirurgi

DOI:
10.3791/60292-v

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08:05 min

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November 08, 2019

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, , , , , , , ,
1Department of Microsurgery,Jesús Usón Minimally Invasive Surgery Centre, 2Stem Cell Therapy Unit,Jesús Usón Minimally Invasive Surgery Centre, 3Animal Modelling Unit,Jesús Usón Minimally Invasive Surgery Centre

Capítulos

  • 00:04Título
  • 01:26Free Skin Flap Model Surgery
  • 03:00Intraoperative Assessment
  • 05:18Postoperative Assessment and Tissue Sampling
  • 06:00Results: Ischemia-Reperfusion Injury in Reconstructive Microsurgery
  • 07:03Conclusion

Summary

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Tadução automática

Her beskriver vi en præklinisk dyremodel for at studere patofysiologien af iskæmi-reperfusion skade i rekonstruktiv mikrokirurgi. Denne gratis hud flap model baseret på de overfladiske hale epigastriske fartøjer i rotter kan også give mulighed for evaluering af forskellige terapier og forbindelser til at modvirke iskæmi-reperfusion skade-relaterede skader.

Tags

Pre-clinical Rat ModelIschemia-reperfusion InjuryReconstructive MicrosurgeryFlap FailureSuperficial Caudal Epigastric VesselsIschemiaReperfusionMicrosurgical ReconstructionInnate ImmunityVascular PedicleMicrocirculatory PerfusionMicrovascular AnastomosisTransit-time Ultrasound Flowmetry

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