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氯乙烯和高脂肪饮食作为环境与肥胖相互作用的典范
JoVE Journal
Medicina
This content is Free Access.
JoVE Journal Medicina
Vinyl Chloride and High-Fat Diet as a Model of Environment and Obesity Interaction
DOI:

09:15 min

January 12, 2020

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Capítulos

  • 00:04Título
  • 00:42Experimental Setup and Purified Experimental Diet Acclimatization
  • 01:21Vinyl Chloride (VC) Inhalation Exposure System Setup
  • 02:17Pre-Exposure Setup
  • 03:21Exposure Experiment and VC Concentration Validation
  • 06:12Post-Exposure
  • 07:01Results: Representative Effects of VC on the Enhancement of Diet-Induced Liver Injury
  • 08:29Conclusion

Summary

Tadução automática

该协议的目标是开发一种低水平毒性暴露的鼠模型,不会造成公开肝损伤,反而会加剧先前存在的肝损伤。这种模式更好地概括了人类接触和接触被认为是安全的毒物浓度时发生的微妙变化。

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