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1Sheikh Zayed Institute for Pediatric Surgical Innovation,Children’s National Hospital, 2Children’s National Heart Institute,Children’s National Hospital, 3Center for Neuroscience Research,Children’s National Hospital, 4Department of Biomedical Engineering, School of Engineering,University of Alabama at Birmingham, 5Department of Pediatrics, Department of Pharmacology & Physiology, School of Medicine and Health Sciences,George Washington University
Capítulos
- 00:05Título
- 01:02Heart Excision and Langendorff Perfusion
- 02:42Electrophysiology Study
- 05:17Transmembrane Voltage and Intracellular Calcium Optical Mapping
- 06:55Cleanup
- 07:20Results: Representative Optical Data from Langendorff-Perfused Model Hearts
- 08:59Conclusion
Formålet med denne undersøgelse var at etablere en metode til undersøgelse af hjertets dynamik ved hjælp af en translationel dyremodel. Den beskrevne eksperimentelle tilgang inkorporerer Dual-emission optocardiography i forbindelse med en elektrofysiologisk undersøgelse for at vurdere elektrisk aktivitet i en isoleret, intakt svine hjerte model.
