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心筋機械変形(DIAMOND)の変位解析は、胚性ゼブラフィッシュにおける心機能のセグメント的不均一性を明らかにする
JoVE Journal
Biologia do Desenvolvimento
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JoVE Journal Biologia do Desenvolvimento
Displacement Analysis of Myocardial Mechanical Deformation (DIAMOND) Reveals Segmental Heterogeneity of Cardiac Function in Embryonic Zebrafish
DOI:

09:15 min

February 06, 2020

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Capítulos

  • 00:04Introduction
  • 01:13Reconstruction of the 3D Systolic and Diastolic Heart and Segmentation of the Ventricle
  • 02:41Creation of Rectangular Parallelepipeds for Image Registration and Resampling of Systolic and Diastolic 3D Hearts Along the Short Axis Plane
  • 05:01Division of the Resampled Heart
  • 06:20Registration of Systolic and Diastolic Image Matrices and Output of Displacement Vectors
  • 07:01Results: Segmental Heterogeneity in Cardiac Function and Susceptibility to Chemotherapy-induced Injury
  • 08:45Conclusion

Summary

Tadução automática

このプロトコルの目標は、生理学的および病理学的条件の下で胚性ゼブラフィッシュにおけるセグメント性心機能の評価のための新しい方法を詳述することです。

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