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Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface
 

Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface

Article DOI: 10.3791/60572-v • 10:10 min • February 23rd, 2020
February 23rd, 2020 •
1, 2, 3, 2, 5, 3,4, 2, 2, 1, 3,4, 1,2
1Bundeswehr Institute of Pharmacology and Toxicology, 2Walther Straub Institute of Pharmacology and Toxicology, University of Munich, 3Cultex Laboratories GmbH, 4Cultex Technologies GmbH (formerly Cultex Laboratories GmbH), 5seh consulting + services

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We present a robust, transferable and predictive in vitro exposure system for the screening and monitoring of airborne particles concerning their acute pulmonary cytotoxicity by exposing cultivated human lung cells at the air-liquid interface (ALI).

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Keywords: Acute Inhalation Toxicity Airborne Particles Cultivated Human Lung Cells Air-liquid Interface In Vitro Exposure System Radial Aerosol Distribution A549 Cells Cell Culture Inserts Compressed Air Pressure Particulate Exposures
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