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小鼠下肢诱导继发性淋巴水肿的修订方法

JoVE Journal
Medicina
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JoVE Journal Medicina

A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice

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小鼠下肢诱导继发性淋巴水肿的修订方法

DOI:

10.3791/60578-v

•

09:50 min

•

November 02, 2019

•

Alexander Wiinholt², Mads G. Jørgensen, Amar Bučan², Farima Dalaei², Jens A. Sørensen

¹University of Southern Denmark, ²Department of Plastic Surgery,Odense University Hospital

Capítulos

00:00Título
00:50Pre-surgery Irradiation
01:36Preparation
02:38Surgery
07:09Post-Surgery Irradiation
07:19Resultados
09:06Conclusion

Summary

Tadução automática

这种动物模型使研究人员能够诱导具有统计学意义的继发性淋巴水肿在小鼠的后肢，持续至少8周。该模型可用于研究淋巴水肿的病理生理学，并研究新的治疗方案。

Tags

Secondary Lymphedema Hindlimb Mice Microsurgery Radiation Anesthesia Saline Surgical Procedure Skin Incision Sciatic Vein

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