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用于测试（新）辅助疗法的不完全切除软组织肉瘤的小鼠模型

JoVE Journal
Medicina

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JoVE Journal Medicina

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies

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用于测试（新）辅助疗法的不完全切除软组织肉瘤的小鼠模型

DOI:

10.3791/60882-v

•

07:15 min

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July 28, 2020

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Francois X. Rwandamuriye², Breana J. Weston³, Terrance G. Johns, W. Joost Lesterhuis², Rachael M. Zemek

¹School of Biomedical Sciences,University of Western Australia, ²Telethon Kids Institute,University of Western Australia, ³College of Science, Health, Engineering and Education,Murdoch University

Capítulos

00:04Introduction
00:56Set-up for Partial Surgical Resection of the Tumor
02:23Partial Surgical Resection of the Tumor
04:20Recovery of Mice and Adjuvant or Neoadjuvant Treatment
05:35Results: Tumor Regrowth Following Incomplete Tumor Resection and Immunotherapy
06:35Conclusion

Summary

Tadução automática

在该协议中，我们描述了一个小鼠模型，不完整的手术切除软组织肉瘤测试（新）辅助疗法。

Tags

Keyword Extract:Mouse Model (neo)adjuvant Therapies Residual Disease Tumor Debulking Surgery Wound Healing Preclinical Studies Cancer Relapse Subcutaneous Inoculation Tumor Resection Anesthesia Surgical Procedure Tumor Exposure Wound Inversion

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