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A Rabbit Venous Interposition Model Mimicking Revascularization Surgery using Vein Grafts to Assess Intimal Hyperplasia under Arterial Blood Pressure
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JoVE Journal Medicina
A Rabbit Venous Interposition Model Mimicking Revascularization Surgery using Vein Grafts to Assess Intimal Hyperplasia under Arterial Blood Pressure

A Rabbit Venous Interposition Model Mimicking Revascularization Surgery using Vein Grafts to Assess Intimal Hyperplasia under Arterial Blood Pressure

DOI:
10.3791/60931-v

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07:02 min

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May 15, 2020

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, ,
1Department of Cardiovascular Surgery, Graduate School of Medicine,Kyoto University, 2Clinical Translational Research Program,RIKEN Center for Biosystems Dynamics Research, 3Department of Cardiovascular Surgery,Takamatsu Red Cross Hospital

Capítulos

  • 00:04Introduction
  • 01:06Jugular Vein Harvest
  • 02:48Carotid Artery Interposition
  • 05:33Results: Representative Effects of Nanoparticle-Loaded miRNA Treatment on Intimal Hyperplasia
  • 06:32Conclusion

Summary

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The present protocol aims to experimentally create venous intimal hyperplasia by subjecting veins to arterial blood pressure for developing strategies to attenuate venous intimal hyperplasia following revascularization surgery using vein grafts.

Tags

RabbitVenous Interposition ModelRevascularization SurgeryVein GraftsIntimal HyperplasiaArterial Blood PressureCardiovascular SurgeryArteriovenous FistulasEnd-stage Renal DiseaseJugular VeinCarotid ArteryHeparin Sodium

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