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毛细管气溶胶发生器在连续生产受控气溶胶中的应用，用于非临床研究
JoVE Journal
Engenharia
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JoVE Journal Engenharia
Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies
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毛细管气溶胶发生器在连续生产受控气溶胶中的应用，用于非临床研究

DOI:
10.3791/61021-v

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08:33 min

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April 12, 2022

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, , , , , , , , ,
1PMI R&D,Philip Morris Products S.A., 2PMI R&D,Philip Morris Research Laboratories Pte. Ltd., 3Applied Mathematics,University of Twente

Capítulos

  • 00:04Introduction
  • 01:08CAG System Assembly
  • 03:14Calculation of CAG Aerosol Concentration and Dilution
  • 04:12CAG Aerosol Generation
  • 05:28Determination of Aerosol Collected Mass (ACM)
  • 06:32Results: Reproducibility and Particle Size Distribution of CAG Generated Aerosols
  • 07:49Conclusion

Summary

Tadução automática

Tadução automática

该协议描述了毛细管气溶胶发生器的设置和使用，用于从多物种液体溶液中连续产生受控气溶胶，适用于稳定的大体积气溶胶输送（例如， 体内 吸入研究）。

Tags

Capillary Aerosol GeneratorCAGAerosol GenerationInhalation ToxicologyElectronic CigaretteLiquid CompositionTemperature ControlAir FlowNucleationCondensationProtocolAssemblyHeating ElementsThermocouplePush-in FittingsO-ringsPeak AdapterCouplingPeristaltic PumpCompressed Air

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