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重症监护病房型装置在猪模型急性呼吸窘迫综合征中的卤化剂递送

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Medicina

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JoVE Journal Medicina

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device

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重症监护病房型装置在猪模型急性呼吸窘迫综合征中的卤化剂递送

DOI:

10.3791/61644-v

•

09:36 min

•

September 24, 2020

•

Raiko Blondonnet², Bertille Paquette², Jules Audard², Ridvan Guler², François-Xavier Roman², Ruoyang Zhai, Corinne Belville, Loïc Blanchon, Thomas Godet, Emmanuel Futier², Jean-Etienne Bazin, Jean-Michel Constantin, Vincent Sapin⁴, Matthieu Jabaudon^2,5

¹Department of Perioperative Medicine,CHU Clermont-Ferrand, ²GReD, CNRS, INSERM,Université Clermont Auvergne, ³GRC 29, AP-HP, DMU DREAM, Department of Anesthesiology and Critical Care, Pitié-Salpêtrière Hospital,Sorbonne University, ⁴Department of Biochemistry and Molecular Genetics,CHU Clermont-Ferrand, ⁵Division of Allergy, Pulmonary, and Critical Care Medicine,Vanderbilt University Medical Center

Capítulos

00:04Introduciton
00:58Animal Preparation
02:27Acid-Induced Acute Lung Injury
03:04Mechanical Ventilation and Halogenated Anesthetics
05:16Monitoring
07:08Results: Representative Porcine Acute Respiratory Distress Syndrome (ARDS) Evaluation
08:59Conclusion

Summary

Tadução automática

我们描述了盐酸诱导的急性呼吸窘迫综合征（ARDS）的模型，该模型通过用于吸入重症监护镇静剂的装置接受卤化剂，异氟醚和七氟醚镇静的仔猪。该模型可用于研究卤化剂对肺损伤和修复的生物学机制。

Tags

Keywords: Porcine Model Acute Respiratory Distress Syndrome Halogenated Agent ICU Device Central Venous Access Femoral Artery Acid-induced Lung Injury Mechanical Ventilation

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