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1Department of Perioperative Medicine,CHU Clermont-Ferrand, 2GReD, CNRS, INSERM,Université Clermont Auvergne, 3GRC 29, AP-HP, DMU DREAM, Department of Anesthesiology and Critical Care, Pitié-Salpêtrière Hospital,Sorbonne University, 4Department of Biochemistry and Molecular Genetics,CHU Clermont-Ferrand, 5Division of Allergy, Pulmonary, and Critical Care Medicine,Vanderbilt University Medical Center
Capítulos
- 00:04Introduciton
- 00:58Animal Preparation
- 02:27Acid-Induced Acute Lung Injury
- 03:04Mechanical Ventilation and Halogenated Anesthetics
- 05:16Monitoring
- 07:08Results: Representative Porcine Acute Respiratory Distress Syndrome (ARDS) Evaluation
- 08:59Conclusion
We describe a model of hydrochloric acid-induced acute respiratory distress syndrome (ARDS) in piglets receiving sedation with halogenated agents, isoflurane and sevoflurane, through a device used for inhaled intensive care sedation. This model can be used to investigate the biological mechanisms of halogenated agents on lung injury and repair.
