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通过视运动反应进行视觉功能的行为评估，通过Y迷宫对糖尿病大鼠的认知功能进行行为评估

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JoVE Journal Comportamento

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

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通过视运动反应进行视觉功能的行为评估，通过Y迷宫对糖尿病大鼠的认知功能进行行为评估

DOI:

10.3791/61806-v

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07:41 min

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October 23, 2020

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Kaavya Gudapati*^1,2, Anayesha Singh*^1,3, Danielle Clarkson-Townsend⁴, Stephen Q. Phillips, Amber Douglass, Andrew J. Feola², Rachael S. Allen²

¹Center for Visual and Neurocognitive Rehabilitation,Atlanta VA Medical Center, ²Department of Biomedical Engineering,Georgia Institute of Technology, ³Department of Neuroscience,Emory University, ⁴Gangarosa Department of Environmental Health,Emory University

Capítulos

00:04Introduction
01:01Optomotor Response (OMR) Apparatus Setup
02:24Spatial Frequency Evaluation
03:51Contrast Sensitivity Evaluation
04:41Y-Maze Evaluation
05:54Results: Representative OMR and Y-Maze Analyses of Diabetic Rat Visual and Cognitive Function and Exploratory Behavior Over Time
07:05Conclusion

Summary

Tadução automática

糖尿病导致的眼睛和大脑的神经变性可以通过对啮齿动物进行的行为测试来观察。Y迷宫（空间认知的量度）和光运动反应（视觉功能的度量）都提供了对潜在诊断和治疗的洞察。

Tags

Keywords: Optomotor Response Y-maze Behavioral Assessment Visual Function Cognitive Function Diabetes Rodent Spatial Frequency Virtual Reality

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