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穆林·德克斯特兰硫酸钠诱导结肠炎模型中肠道炎症的系统评分分析

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Imunologia e Infecção

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JoVE Journal Imunologia e Infecção

Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model

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穆林·德克斯特兰硫酸钠诱导结肠炎模型中肠道炎症的系统评分分析

DOI:

10.3791/62135-v

•

09:11 min

•

February 14, 2021

•

Vicky Garcia-Hernandez, Philipp-Alexander Neumann, Stefan Koch⁴, Renae Lyons, Asma Nusrat, Charles A. Parkos

¹Department of Pathology,University of Michigan, ²Department of Surgery, Klinikum Rechts der Isar,Technische Universität München, ³Wallenberg Centre for Molecular Medicine,Linköping University, ⁴Department of Biomedical and Clinical Sciences (BKV),Linköping University

Capítulos

00:04Introduction
00:50Tissue Harvest
02:24Preparation of Swiss Rolls
03:57Digital Scanning and Analysis
06:33Results: Histological Colitis Score and Percentage of Injury and Ulceration Correlates with Body Weight and Stool Index During DSS Experimental Colitis
08:30Conclusion

Summary

Tadução automática

使用免费计算机辅助系统系统地对肠道炎症进行评分，是定量比较以溃疡和炎症变化为特征的结肠炎模型组织病理变化的有力工具。病理结肠炎评分评估加强临床观察，便于数据解释。

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