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Doxycycline Loaded Collagen-Chitosan Composite Scaffold for the Accelerated Healing of Diabetic Wounds
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Bioengenharia
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JoVE Journal Bioengenharia
Doxycycline Loaded Collagen-Chitosan Composite Scaffold for the Accelerated Healing of Diabetic Wounds

Doxycycline Loaded Collagen-Chitosan Composite Scaffold for the Accelerated Healing of Diabetic Wounds

DOI:
10.3791/62184-v

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10:49 min

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August 21, 2021

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, , , , ,
1Department of Pharmaceutics, JSS College of Pharmacy,JSS Academy of Higher Education & Research, 2Department of Pharmaceutical Sciences, School of Pharmacy,North Dakota state university, 3Department of Pharmacology, JSS College of Pharmacy,JSS Academy of Higher Education & Research

Capítulos

  • 00:08Introduction
  • 02:00Methodology
  • 07:54in vivo Studies
  • 09:14Resultados
  • 10:18Conclusion

Summary

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The prepared DOX-CL scaffold satisfied the prerequisites of an ideal DW dressing in mechanical strength, porosity, water absorption, degradation rate, sustained release, anti-bacterial, biocompatibility, and anti-inflammatory properties, which are considered to be essential for the recovery of damaged tissue in DWs.

Tags

Keywords: DoxycyclineCollagen-chitosan ScaffoldDiabetic WoundsWound HealingMMP-9 InhibitorBiomaterialsDrug DeliveryBiomedical DevicesCollagen SolutionChitosan Solution

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