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Injiserbare supramolecular polymer-nanopartikkel hydrogeler for celle- og legemiddelleveringsapplikasjoner
JoVE Journal
Bioengenharia
This content is Free Access.
JoVE Journal Bioengenharia
Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
DOI:

09:39 min

February 07, 2021

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Capítulos

  • 00:04Introduction
  • 00:49Nanoparticle (NP) Synthesis
  • 02:10Hydrogel Formulation and Rheological Property Measurement
  • 03:27In Vitro Drug Release Characterization
  • 04:35Thermal Stability of Gel-Encapsulated Insulin Characterization
  • 05:19Cell Viability Assessment
  • 06:08Cell Settling Assessment
  • 07:15Results: Representative Polymer Nanoparticle (PNP) Hydrogel Release Kinetics, Cargo Stability, and Cell Viability
  • 09:00Conclusion

Summary

Tadução automática

Denne protokollen beskriver syntesen og formuleringen av injiserbare, supramolecular polymer-nanopartikkel (PNP) hydrogelbiomaterialer. Anvendelser av disse materialene for legemiddellevering, biofarmasøytisk stabilisering og celleinnkapsling og levering er demonstrert.

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