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意识约束兔子中癫痫发作、心律失常和呼吸暂停的多系统监测

JoVE Journal
Medicina

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JoVE Journal Medicina

Multi-system Monitoring for Identification of Seizures, Arrhythmias and Apnea in Conscious Restrained Rabbits

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意识约束兔子中癫痫发作、心律失常和呼吸暂停的多系统监测

DOI:

10.3791/62256-v

•

10:25 min

•

March 27, 2021

•

Cameron Bosinski, Kyle Wagner, Xiangping Zhou, Lynn Liu, David S. Auerbach

¹Department of Pharmacology,Upstate Medical University, ²Department of Neurology,Upstate Medical University, ³Strong Epilepsy Center, Departments of Neurology, Anesthesiology / Perioperative Medicine, & Pediatrics,University of Rochester Medical Center

Capítulos

00:04Introduction
00:55Implanting Electroencephalogram (EEG) and Electrocardiogram (ECG) Electrodes and Attaching Respiratory Monitors
02:45Video EEG-ECG Recording
03:32Photic Stimulation
04:59Oral Medication Administration
05:52Intravenous Medication Administration
07:08Analysis of ECG and Video-EEG
08:23Results: Identification of Seizures and Arrhythmias in Conscious Restrained Rabbits
09:41Conclusion

Summary

Tadução automática

我们利用同时进行的视频-EEG-ECG-氧化-量谱-封盖术，开发了一种评估兔子模型易感性的方法，以开发引起心律失常和癫痫发作。这种新型记录系统建立了一个平台，以测试治疗的功效和安全性，并可以捕捉复杂的多系统事件级联，最终导致突然死亡。

Tags

Keywords: Multi-system Monitoring Seizures Arrhythmias Apnea Conscious Restrained Rabbits Cardiac Dysfunction Respiratory Dysfunction Sudden Death Neurologic Function Cardiac Function Respiratory Function ECG Electrodes EEG Electrodes Pulse Oximeter Capnography Video EEG-ECG

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