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1Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt Universität zu Berlin and Berlin Institute of Health Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow-Klinikum, 2Chair for Medical Information Technology,RWTH Aachen University
Capítulos
- 00:05Introduction
- 00:44The Mechanical Ventilation
- 01:46Introduction of the Pulmonary Artery Catheter
- 02:46Surfactant Depletion
- 03:41Injurious Ventilation with High Tidal Volume/Low PEEP (High Tv/low PEEP)
- 04:25Results: Effects of the Injurious Ventilation on the Lungs
- 05:40Conclusion
En kombination af udvaskning af overfladeaktive stoffer med 0,9 % saltvand (35 mL/kg legemsvægt, 37 °C) og ventilation med lavt tidevandsvolumen med lavt PEEP for at forårsage moderat respiratorinduceret lungeskade (VILI) resulterer i eksperimentel akut respiratorisk nødsyndrom (ARDS). Denne metode giver en model af lungeskader med lav / begrænset recruitability at studere effekten af forskellige ventilationsstrategier i længere perioder.
