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A Protocol for Roux-en-Y Gastric Bypass in Rats using Linear Staplers
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JoVE Journal Medicina
A Protocol for Roux-en-Y Gastric Bypass in Rats using Linear Staplers

A Protocol for Roux-en-Y Gastric Bypass in Rats using Linear Staplers

DOI:
10.3791/62575-v

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11:58 min

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August 21, 2021

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, , , , , ,
1Department of Surgery,University of Alberta, 2Faculty of Medicine and Dentistry,University of Alberta, 3Department of Medicine,University of Alberta

Capítulos

  • 00:13Introduction
  • 00:39Preparation of Animals and Operative Setup
  • 01:07Median Laparotomy
  • 01:36Mobilizing the Stomach
  • 02:42Identify and Divide the Jejunum
  • 03:52Stapling the Stomach
  • 04:49Gastrojejunostomy
  • 08:24Jejunojejunostomy
  • 09:56Reposition the Bowel and Stomach
  • 10:20Abdominal Closure
  • 10:47Resultados
  • 11:28Conclusion

Summary

Tadução automática

Tadução automática

Roux-en-Y gastric bypass (RYGB) is performed to treat obesity and diabetes. However, the mechanisms underlying RYGB's efficacy are not fully understood, and studies are limited by technical difficulty leading to high mortality in animal models. This article provides instructions on how to perform RYGB in rats with high success rates.

Tags

Keywords: Roux-en-y Gastric BypassRat ModelObesityType 2 DiabetesLaparotomyStomach MobilizationJejunumMesenteryLinear Stapler

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