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大鼠模型中的视网膜病理生理学评估
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JoVE Journal Medicina
Retinal Pathophysiological Evaluation in a Rat Model
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大鼠模型中的视网膜病理生理学评估

DOI:
10.3791/63111-v

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09:11 min

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May 06, 2022

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1Translational Pharmaceutics Research Laboratory (TPRL), Department of Pharmacy,Birla Institute of Technology & Science — Pilani, Hyderabad Campus

Capítulos

  • 00:09Introduction
  • 01:11Retinal Histology
  • 03:40Blood Retinal Barrier Breakdown Assay
  • 05:15Fluorescence Angiography
  • 07:09Representative Results
  • 08:40Conclusion

Summary

Tadução automática

Tadução automática

糖尿病视网膜病变是失明的主要原因之一。组织学、血液-视网膜屏障破坏测定和荧光血管造影是了解视网膜病理生理学的宝贵技术，可以进一步提高针对糖尿病视网膜病变的药物筛查效率。

Tags

Keywords: Retinal PathophysiologyDiabetic RetinopathyStreptozotocin-induced Diabetic RetinopathyRat ModelHistologyBRB Breakdown AssayFluorescein AngiographyFITC-dextranEnucleationFixationDehydrationParaffin EmbeddingMicrotome

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