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Ex Vivo and In Vivo Animal Models for Mechanical and Chemical Injuries of Corneal Epithelium
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JoVE Journal Medicina
Ex Vivo and In Vivo Animal Models for Mechanical and Chemical Injuries of Corneal Epithelium

Ex Vivo and In Vivo Animal Models for Mechanical and Chemical Injuries of Corneal Epithelium

DOI:
10.3791/63217-v

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07:10 min

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April 06, 2022

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,
1Department of Ophthalmology,Chang-Gung Memorial Hospital, 2Chang-Gung University College of Medicine, 3Institute of Clinical Medicine,National Yang Ming Chiao Tung University

Capítulos

  • 00:04Introduction
  • 00:34Ex Vivo Wound Healing Model of Mouse Corneal Epithelium
  • 03:13In Vivo Rabbit Model of Corneal Alkali Injury
  • 05:05Results: Mechanical and Chemical Injury of Corneal Epithelium in Animal Models
  • 06:26Conclusion

Summary

Tadução automática

Tadução automática

Here, animal models based on mouse and rabbit are developed for mechanical and chemical injury of corneal epithelium to screen new therapeutics and the underlying mechanism.

Tags

Ex VivoIn VivoAnimal ModelsMechanical InjuryChemical InjuryCorneal EpitheliumMurine Corneal Epithelial WoundCorneal AbrasionEx Vivo CultureEyeballCorneal ScissorsCorneal ForcepsFluorescein StainingAlkaline Burn InjurySodium Hydroxide

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