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Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
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Neurociência
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JoVE Journal Neurociência
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

DOI:
10.3791/63442-v

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10:10 min

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February 15, 2022

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, , , , ,
1Instituto de Biofísica Carlos Chagas Filho,Universidade Federal do Rio de Janeiro

Capítulos

  • 00:05Introduction
  • 00:57Ocular Hypertension Surgery and Clinical Follow-up
  • 02:53Optomotor Response Analysis and Recording of Pattern-Electroretinogram
  • 04:04Quantification of Retinal Ganglion Cell Somas
  • 05:38Examination of the Optic Nerve
  • 07:33Results: Characterization of Glaucomatous Neurodegeneration by Limbal Vascular Plexus Cauterization
  • 09:26Conclusion

Summary

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The goal of this protocol is to characterize a novel model of glaucomatous neurodegeneration based on 360° thermic cauterization of limbal vascular plexus, inducing subacute ocular hypertension.

Tags

Keywords: GlaucomaLimbal Vascular PlexusIntraocular PressureOptic NerveRetinaCauterizationRodentsAnimal ModelNeurodegenerative DisordersTopical MedicationsOptomotor Response

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