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Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection
JoVE Journal
Imunologia e Infecção
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JoVE Journal Imunologia e Infecção
Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection
DOI:

09:24 min

April 06, 2022

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Capítulos

  • 00:04Introduction
  • 00:50Infection of C. elegans with N. Parisiito Yield Immune-Primed Offspring
  • 03:30Testing Inherited Immunity to N. Parisii de C. elegans and Analysis of DY96-Stained Worms to Assess Infection Status
  • 06:10Results: Study of Inherited Immunity in Genetically Tractable Worm Model
  • 08:32Conclusion

Summary

Tadução automática

The infection of Caenorhabditis elegans by the microsporidian parasite Nematocida parisii enables the worms to produce offspring that are highly resistant to the same pathogen. This is an example of inherited immunity, a poorly understood epigenetic phenomenon. The present protocol describes the study of inherited immunity in a genetically tractable worm model.

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