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绵羊眼玻璃体内注射

JoVE Journal
Medicina

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JoVE Journal Medicina

Intravitreal Injections in the Ovine Eye

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绵羊眼玻璃体内注射

DOI:

10.3791/63823-v

•

03:37 min

•

July 05, 2022

•

Samantha J. Murray, Nadia L. Mitchell

¹Faculty of Agriculture and Life Sciences,Lincoln University

Capítulos

00:05Introduction
00:52Surgical Procedure
01:30Viral Administration
02:11Results: ERG Response, Retinal Thickness, and GFAP Immunoreactivity in CLN5 Sheep Retina after AAV9•CLN5• Administration
03:05Conclusion

Summary

Tadução automática

在羊眼中进行玻璃体内注射，目的是将病毒介导的基因治疗传递到视网膜。

Tags

Intravitreal Injections Sheep Eye Gene Therapy Retinal Degeneration Neuronal Ceroid Lipofuscinoses Povidone Iodine Electroretinography Retinal Histology GFAP Therapeutic Agents Vitreous Humor

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